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What it is
Vasoactive intestinal peptide, called VIP for short, is a neuropeptide, a small protein-like messenger released by nerve cells. It is made of 28 amino acids and is found in nerves of the gut, lungs, and brain.
Why researchers study it
Researchers study VIP in animal models of the intestinal barrier, the cell layer that controls what passes from the gut into the body. Mice bred to lack VIP entirely let researchers measure what changes when this one messenger is missing.
Study spotlight
In VIP-deficient mice, researchers examined colon crypt structure, barrier permeability, goblet cell numbers, and responses in two colitis models. The paper reported distorted crypts, altered permeability, and more severe colitis in VIP-deficient mice, and that VIP administration protected those mice in one model.
Read the study: https://pubmed.ncbi.nlm.nih.gov/25932952/
Vasoactive Intestinal Peptide (VIP) is a neuropeptide compound.
Supplied lyophilized at 5mg with bacteriostatic water.
Store in a cool, dry place away from direct light.
Mixing this vial? Get your syringe units in seconds with the free Peptide Reconstitution Calculator.
For Laboratory use only.
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